Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | UBE2M | P61081 | 3/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24448475 | 0.85 | UBE2M (0.34) | ROCK2TP53UBE2MDCUN1D1MKNK1 | |
| SCHEMBL23905504 | 0.79 | NR1H4 (0.52) | NPSR1RXFP1NR1H4TP53UBE2M | |
| SCHEMBL23904810 | 0.78 | UBE2M (0.44) | NPSR1RXFP1NR1H4TP53UBE2M | |
| SCHEMBL20049214 | 0.77 | MAPT (0.53) | NPSR1RXFP1TP53ACHEHSD17B10 | |
| SCHEMBL6172529 | 0.77 | ALDH1A1 (0.58) | NPSR1TP53UBE2MDCUN1D1HSD17B10 | |
| SCHEMBL13826794 | 0.76 | TP53 (0.41) | TP53UBE2MDCUN1D1MAPTTSHR | |
| SCHEMBL2664863 | 0.74 | HSD17B10 (0.64) | TP53ACHEHSD17B10MAPTTSHR | |
| SCHEMBL20049114 | 0.72 | ACHE (0.37) | NPSR1RXFP1ACHEHSD17B10MAPT | |
| SCHEMBL21328395 | 0.71 | UBE2M (0.41) | ROCK2NPSR1RXFP1NR1H4TP53 | |
| SCHEMBL6172975 | 0.69 | ALDH1A1 (0.44) | TP53UBE2MDCUN1D1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |