SCHEMBL23905295 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	HCAR2	Q8TDS4	1/20	0.38

▸	RECQL	P46063	1/20	0.38

▸	AGBL2	Q5U5Z8	1/20	0.36

▸	PADI4	Q9UM07	5/20	0.34

▸	LMNA	P02545	2/20	0.34

▸	MAPT	P10636	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	HDAC1	Q13547	2/20	0.32

▸	HDAC6	Q9UBN7	2/20	0.32

▸	KDM1A	O60341	1/20	0.32

▸	PTGS2	P35354	2/20	0.31

▸	PTGDR2	Q9Y5Y4	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23904777	0.83	MTNR1A (0.33)	HCAR2LMNAMAPTSMN1; SMN2
SCHEMBL23905507	0.83	APP (0.47)	RECQLAGBL2MAPTSMN1; SMN2PTGS2
SCHEMBL2171291	0.78	MEN1 (0.50)	RECQLLMNAMAPT
SCHEMBL2171297	0.78	MEN1 (0.50)	RECQLLMNAMAPT
SCHEMBL1915837	0.72	RECQL (0.69)	RECQLMAPT
SCHEMBL1915838	0.72	RECQL (0.69)	RECQLMAPT
SCHEMBL1915834	0.72	RECQL (0.69)	RECQLMAPT
SCHEMBL7132118	0.70	RECQL (0.51)	RECQLLMNAMAPT
SCHEMBL7617840	0.69	GSK3B (0.50)	RECQLLMNAMAPTSMN1; SMN2HDAC1
SCHEMBL17255821	0.69	KDM4E (0.50)	HCAR2PADI4MAPTSMN1; SMN2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021198981-A1	ANTIVIRAL COMPOUNDS AND USES THEREOF	Janssen Biopharma, Inc. (US)	2021-10-07	—	—	WO	disclosed