Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905512 | 0.85 | APP (0.43) | APPPTGS2ALDH1A1HPGDGPR35 | |
| SCHEMBL23905295 | 0.83 | HCAR2 (0.38) | PTGS2AGBL2RECQLMAPTSMN1; SMN2 | |
| SCHEMBL3959782 | 0.81 | RECQL (0.46) | ALDH1A1RECQLMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL3959783 | 0.81 | RECQL (0.46) | ALDH1A1RECQLMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL3310234 | 0.74 | RECQL (0.37) | APPPTGS2RECQLHPGDMAPT | |
| SCHEMBL12498149 | 0.74 | AKR1C3 (0.43) | APPAGBL2ALDH1A1TAS2R14HPGD | |
| SCHEMBL12498144 | 0.74 | AKR1C3 (0.43) | APPAGBL2ALDH1A1TAS2R14HPGD | |
| SCHEMBL12498146 | 0.71 | APP (0.60) | APPALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3311082 | 0.71 | NPFFR1 (0.43) | APPRECQLKDM4EMAPTL3MBTL1 | |
| SCHEMBL23904777 | 0.70 | MTNR1A (0.33) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |