Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904777 | 0.86 | MTNR1A (0.33) | MAPTLMNA | |
| SCHEMBL23905507 | 0.85 | APP (0.47) | APPARPTGS2L3MBTL1PSEN1 | |
| SCHEMBL1914722 | 0.73 | RECQL (0.46) | MEN1KMT2AMAPT | |
| SCHEMBL1914726 | 0.73 | RECQL (0.46) | MEN1KMT2AMAPT | |
| SCHEMBL4298399 | 0.71 | TUBB1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4298394 | 0.71 | TUBB1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2875911 | 0.69 | RECQL (0.42) | PTGS2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL23905295 | 0.69 | HCAR2 (0.38) | PTGS2MAPTLMNA | |
| SCHEMBL12498146 | 0.68 | APP (0.60) | APPALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL17242706 | 0.67 | KDM4E (0.50) | APPARALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |