Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 16/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905554 | 0.89 | ACACB (0.42) | NR1H4ACACB | |
| SCHEMBL23905542 | 0.87 | ACACB (0.39) | ACACBKMT2A | |
| SCHEMBL23905899 | 0.80 | NR1H4 (0.41) | NR1H4KMT2A | |
| SCHEMBL22672605 | 0.73 | TOP2A (0.40) | NR1H4ACACB | |
| SCHEMBL23904848 | 0.72 | KMO (0.37) | KMT2A | |
| SCHEMBL22672569 | 0.71 | CA12 (0.45) | NR1H4 | |
| SCHEMBL22672718 | 0.70 | TOP2A (0.41) | NR1H4KMT2A | |
| SCHEMBL22672407 | 0.70 | NR1H4 (0.38) | NR1H4 | |
| SCHEMBL25114764 | 0.70 | KMT2A (0.36) | ACACBKMT2A | |
| SCHEMBL20833630 | 0.70 | NPC1 (0.43) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |