Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905549 | 0.89 | NR1H4 (0.40) | ACACBNR1H4 | |
| SCHEMBL23905542 | 0.88 | ACACB (0.39) | ACACBPDE4B | |
| SCHEMBL20833630 | 0.72 | NPC1 (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20833809 | 0.71 | CYP2C9 (0.42) | — | |
| SCHEMBL23905899 | 0.69 | NR1H4 (0.41) | NR1H4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22945940 | 0.69 | LMNA (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23905898 | 0.69 | RAB9A (0.38) | ACACBNR1H4PDE4APDE4BPDE4C | |
| SCHEMBL23905552 | 0.69 | NPC1 (0.38) | NR1H4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23905759 | 0.68 | NPC1 (0.38) | NR1H4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22672605 | 0.65 | TOP2A (0.40) | ACACBNR1H4PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |