Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905898 | 0.87 | RAB9A (0.38) | NR1H4KMT2AHDAC6PDE4APDE4B | |
| SCHEMBL23905466 | 0.82 | CA12 (0.45) | NR1H4KMT2AHDAC6TOP2A | |
| SCHEMBL23905549 | 0.80 | NR1H4 (0.40) | NR1H4KMT2A | |
| SCHEMBL23195951 | 0.73 | CCR1 (0.39) | NR1H4KMT2APDE4APDE4BPDE4C | |
| SCHEMBL23905757 | 0.72 | KMT2A (0.38) | NR1H4KMT2APDE4APDE4BPDE4C | |
| SCHEMBL25113847 | 0.71 | CA12 (0.45) | NR1H4KMT2A | |
| SCHEMBL23905513 | 0.70 | ALDH1A1 (0.43) | KMT2AHDAC6 | |
| SCHEMBL20833630 | 0.70 | NPC1 (0.43) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22672677 | 0.70 | TOP2A (0.38) | NR1H4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20833809 | 0.69 | CYP2C9 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |