Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642227 | 0.79 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1GLAHPGDPOLB | |
| SCHEMBL16876938 | 0.73 | OPRL1 (0.40) | LMNAKCNH2HRH3L3MBTL1OPRL1 | |
| SCHEMBL2394398 | 0.72 | OPRL1 (0.36) | LMNAKCNH2HRH3OPRL1OPRM1 | |
| SCHEMBL2388734 | 0.72 | OPRL1 (0.36) | LMNAKCNH2HRH3OPRL1OPRM1 | |
| SCHEMBL2391602 | 0.69 | SLC1A2 (0.37) | LMNAALDH1A1POLB | |
| SCHEMBL6185831 | 0.68 | TMEM97 (0.38) | LMNAOPRL1OPRM1 | |
| SCHEMBL2389761 | 0.68 | CYP3A4 (0.41) | LMNAALDH1A1GLAHPGD | |
| SCHEMBL23459249 | 0.68 | FKBP1A (0.38) | ALDH1A1 | |
| SCHEMBL2395154 | 0.68 | OPRM1 (0.39) | LMNAALDH1A1OPRL1OPRM1 | |
| SCHEMBL2390992 | 0.67 | KDM4E (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013008-B2 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-09-06 | — | — | US | disclosed |