Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | RHOC | P08134 | 1/20 | 0.31 |
| ▸ | RHOA | P61586 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | GIPR | P48546 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905651 | 0.92 | ROCK2 (0.33) | ADRA1DADRA1AADRA1BGCGRROCK2 | |
| SCHEMBL23905736 | 0.87 | SLC5A7 (0.32) | P2RX7 | |
| SCHEMBL23905961 | 0.85 | MAPT (0.32) | ADRA1DADRA1AADRA1BGCGRROCK2 | |
| SCHEMBL23905464 | 0.84 | ROCK2 (0.33) | ROCK2ROCK1MAPTPDE4BP2RX7 | |
| SCHEMBL23905666 | 0.84 | ROCK2 (0.33) | GCGRROCK2ROCK1MAPTPDE4B | |
| SCHEMBL23195972 | 0.83 | TP53 (0.32) | ROCK2ROCK1MAPTP2RX7THRB | |
| SCHEMBL23905636 | 0.82 | POLB (0.33) | MAPT | |
| SCHEMBL23905459 | 0.81 | POLB (0.36) | ROCK2ROCK1MAPTP2RX7HCRTR1 | |
| SCHEMBL23904908 | 0.76 | MAPT (0.35) | ROCK2ROCK1MAPTPDE4BALOX5 | |
| SCHEMBL23904817 | 0.76 | LRRK2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |