Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MTTP | P55157 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905666 | 0.92 | ROCK2 (0.33) | ROCK2ROCK1PDE4BMAPTPIK3CD | |
| SCHEMBL23905651 | 0.92 | ROCK2 (0.33) | ROCK2ROCK1PDE4BP2RX7MAPT | |
| SCHEMBL23905459 | 0.89 | POLB (0.36) | ROCK2ROCK1P2RX7MAPTMTTP | |
| SCHEMBL23905558 | 0.88 | GABRA5 (0.31) | — | |
| SCHEMBL23905650 | 0.84 | ADRA1D (0.33) | ROCK2ROCK1PDE4BP2RX7MAPT | |
| SCHEMBL23904817 | 0.84 | LRRK2 (0.34) | LRRK2 | |
| SCHEMBL23905661 | 0.83 | LMNA (0.33) | MAPT | |
| SCHEMBL24345454 | 0.83 | POLB (0.38) | P2RX7 | |
| SCHEMBL24363611 | 0.83 | POLB (0.38) | P2RX7 | |
| SCHEMBL23905662 | 0.80 | GABRA5 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |