Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | STAMBP | O95630 | 1/20 | 0.48 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16533300 | 0.86 | ALOX15 (0.58) | HPGDSDYRK1AKMT2AMEN1HPGD | |
| SCHEMBL16517662 | 0.84 | KMT2A (0.52) | HPGDSDYRK1AKMT2AMEN1HPGD | |
| SCHEMBL23905397 | 0.83 | HPGDS (0.51) | HPGDSDYRK1AKMT2AMEN1HPGD | |
| SCHEMBL30211275 | 0.83 | MAPT (0.53) | HPGDSDYRK1AKMT2AMEN1HPGD | |
| SCHEMBL16533611 | 0.83 | KMT2A (0.51) | HPGDSDYRK1AKMT2AMEN1HPGD | |
| SCHEMBL18548565 | 0.81 | KMT2A (0.49) | HPGDSDYRK1AKMT2AMEN1HPGD | |
| SCHEMBL27976330 | 0.81 | KMT2A (0.52) | HPGDSDYRK1AKMT2AMEN1HPGD | |
| SCHEMBL1225083 | 0.78 | HSD17B2 (0.51) | HPGDSDYRK1AKMT2AMEN1HPGD | |
| SCHEMBL20292775 | 0.76 | DYRK1A (1.00) | HPGDSDYRK1A | |
| SCHEMBL30134451 | 0.75 | KMT2A (0.58) | HPGDSKMT2AMEN1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |