Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | STAMBP | O95630 | 1/20 | 0.43 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23195925 | 0.86 | HTT (0.51) | MEN1HPGDKMT2APSMD14PDE4D | |
| SCHEMBL23195592 | 0.85 | LMNA (0.44) | PDE4DHRH1KCNH2LMNACYP3A4 | |
| SCHEMBL29620722 | 0.85 | LMNA (0.44) | PDE4DHRH1KCNH2LMNACYP3A4 | |
| SCHEMBL23905676 | 0.83 | HPGDS (0.67) | HPGDSPLK1DYRK1ASMN1; SMN2MEN1 | |
| SCHEMBL23166684 | 0.82 | HRH1 (0.45) | POLBHRH1KCNH2CYP3A4CYP2D6 | |
| SCHEMBL23905326 | 0.81 | HRH1 (0.41) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL23905722 | 0.81 | HPGDS (0.45) | HPGDSHPGDPSMD14STAMBPCOPS5 | |
| SCHEMBL22428729 | 0.75 | HRH1 (0.48) | PDE4DHRH1KCNH2CYP3A4CYP2D6 | |
| SCHEMBL30873829 | 0.75 | HRH1 (0.48) | PDE4DHRH1KCNH2CYP3A4CYP2D6 | |
| SCHEMBL30744840 | 0.74 | KMO (0.44) | PSMD14PDE4DPOLBKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |