Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | MTTP | P55157 | 3/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905710 | 0.85 | POLB (0.34) | POLBKMT2AMEN1HPGDMAPT | |
| SCHEMBL23905515 | 0.83 | POLB (0.37) | POLBKMT2AMEN1HPGDDYRK1A | |
| SCHEMBL23905459 | 0.82 | POLB (0.36) | POLBKMT2AMEN1HPGDMAPT | |
| SCHEMBL24345844 | 0.82 | POLB (0.36) | POLBKMT2AMEN1HPGDDYRK1A | |
| SCHEMBL24345474 | 0.82 | POLB (0.35) | POLBKMT2AMEN1HPGDDYRK1A | |
| SCHEMBL24345317 | 0.80 | POLB (0.34) | POLBKMT2AMEN1HPGDMAPT | |
| SCHEMBL23905829 | 0.79 | ROCK2 (0.31) | CTSAMAPTROCK2ROCK1 | |
| SCHEMBL23905665 | 0.77 | MAPT (0.33) | POLBMAPTROCK2ROCK1 | |
| SCHEMBL24345454 | 0.76 | POLB (0.38) | POLBKMT2AMEN1HPGDDYRK1A | |
| SCHEMBL24363611 | 0.76 | POLB (0.38) | POLBKMT2AMEN1HPGDDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |