Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905747 | 0.84 | TP53 (0.42) | PDE4DLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL29620722 | 0.82 | LMNA (0.44) | KMOPDE4DLMNAMETAP2METAP1 | |
| SCHEMBL23195592 | 0.82 | LMNA (0.44) | KMOPDE4DLMNAMETAP2METAP1 | |
| SCHEMBL18031358 | 0.80 | MEN1 (0.48) | PDE4DLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL20515873 | 0.80 | PDE4B (0.46) | MAP4K4KMONR1H4PDE4DPDE4A | |
| SCHEMBL23195619 | 0.79 | MAPT (0.48) | LMNAMETAP2METAP1HDAC6PDE4A | |
| SCHEMBL16517662 | 0.78 | KMT2A (0.52) | LMNAMETAP2METAP1HDAC6PDE4A | |
| SCHEMBL16620695 | 0.78 | MEN1 (0.50) | LMNAMETAP2METAP1HDAC6PDE4A | |
| SCHEMBL30744820 | 0.77 | MEN1 (0.55) | LMNAPDE4AKDM4EPOLBMEN1 | |
| SCHEMBL2485757 | 0.76 | MCHR1 (0.58) | PDE4DLMNAPDE4AKDM4EPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |