Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 14/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23195592 | 1.00 | LMNA (0.44) | LMNAMETAP2METAP1HDAC6HRH1 | |
| SCHEMBL30744840 | 0.88 | KMO (0.44) | LMNAMETAP2METAP1HDAC6KCNH2 | |
| SCHEMBL30744828 | 0.87 | PDE4D (0.44) | PDE4APDE4D | |
| SCHEMBL23195925 | 0.86 | HTT (0.51) | LMNAHRH1KCNH2PDE4DCYP3A4 | |
| SCHEMBL23905397 | 0.85 | HPGDS (0.51) | LMNAHRH1KCNH2PDE4DCYP3A4 | |
| SCHEMBL23166684 | 0.84 | HRH1 (0.45) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL23905326 | 0.83 | HRH1 (0.41) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL23905537 | 0.82 | KMO (0.39) | KMOPDE4APDE4D | |
| SCHEMBL23905749 | 0.82 | MAP4K4 (0.45) | LMNAMETAP2METAP1HDAC6KMO | |
| SCHEMBL16517662 | 0.80 | KMT2A (0.52) | LMNAMETAP2METAP1HDAC6PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086840-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |