Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9052784 | 0.98 | MCHR1 (0.57) | MCHR1RAB9AMAPTNPC1LMNA | |
| SCHEMBL2483278 | 0.92 | MCHR1 (0.68) | MCHR1RAB9AMAPTNPC1LMNA | |
| SCHEMBL15603473 | 0.90 | MCHR1 (0.60) | MCHR1RAB9AMAPTNPC1LMNA | |
| SCHEMBL15603446 | 0.84 | RAB9A (0.49) | MCHR1RAB9AMAPTNPC1LMNA | |
| SCHEMBL13738023 | 0.81 | MCHR1 (0.63) | MCHR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9192621 | 0.81 | ALDH1A1 (0.53) | RAB9AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL28195001 | 0.80 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL5188743 | 0.80 | RAB9A (0.50) | RAB9AMAPTNPC1LMNASMN1; SMN2 | |
| SCHEMBL16132600 | 0.77 | MCHR1 (0.59) | MCHR1LMNAKDM4E | |
| SCHEMBL10368023 | 0.77 | RAB9A (0.48) | RAB9AMAPTNPC1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064756-A1 | Use of Alcohol-Oxyalkylates in the Form of Adjuvants for Benzamidoxime Fungicidal Derivatives, Appropriate Agents and Kits | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | claimed |
| EP-0445731-B1 | Azabicyclo and azacyclo oxime and amine cholinergic agents and pharmaceutically acceptable salts thereof | WARNER LAMBERT CO (US) | 1996-01-10 | — | — | EP | claimed |
| US-5482938-A | Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | claimed |
| CN-103492377-A | Triazolopyridine compounds as PIM kinase inhibitors | ARRAY BIOPHARMA INC | 2014-01-01 | — | — | CN | disclosed |
| US-8013153-B2 | Substituted pyrimidine kinase inhibitors | JANSSEN PHARMACEUTICA, N.V. (BE) | 2011-09-06 | — | — | US | disclosed |
| US-20080064756-A1 | Use of Alcohol-Oxyalkylates in the Form of Adjuvants for Benzamidoxime Fungicidal Derivatives, Appropriate Agents and Kits | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | disclosed |
| US-20080064756-A1 | Use of Alcohol-Oxyalkylates in the Form of Adjuvants for Benzamidoxime Fungicidal Derivatives, Appropriate Agents and Kits | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | disclosed |
| US-20070254896-A1 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-11-01 | — | — | US | disclosed |
| CN-1268132-A | Cis-substituted fluoromethylpyrrolidine derivatives | DAIICHI SEIYAKU CO (JP) | 2000-09-27 | — | — | CN | disclosed |
| US-5306718-A | Analgesics, cognition activators | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064756-A1 | Use of Alcohol-Oxyalkylates in the Form of Adjuvants for Benzamidoxime Fungicidal Derivatives, Appropriate Agents and Kits | ADH5, AOX1, CYP2E1 | MCHR1 3837/4885RAB9A 4617/4885MAPT 4379/4885 |
| US-20070254896-A1 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | DTYMK, TK1, DCK | MCHR1 4705/4885RAB9A 2802/4885MAPT 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.