Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905608 | 0.92 | POLB (0.31) | POLBKMT2AMAPT | |
| SCHEMBL23905797 | 0.85 | PTGFR (0.32) | POLBKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23905949 | 0.85 | PTGFR (0.31) | POLBKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23905642 | 0.85 | POLB (0.30) | POLBKMT2AMAPT | |
| SCHEMBL23905254 | 0.82 | POLB (0.32) | POLBKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23905804 | 0.81 | ADRA1D (0.32) | — | |
| SCHEMBL23905641 | 0.81 | LMNA (0.33) | POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23904706 | 0.81 | — | — | |
| SCHEMBL23905947 | 0.80 | — | — | |
| SCHEMBL23904891 | 0.78 | PTGS1 (0.33) | POLBKMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |