Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 3/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905797 | 0.94 | PTGFR (0.32) | PTGFRBTKPOLBKMT2AMAPT | |
| SCHEMBL23905809 | 0.92 | — | — | |
| SCHEMBL23904891 | 0.87 | PTGS1 (0.33) | PTGFRBTKCFTRPOLBKMT2A | |
| SCHEMBL23905782 | 0.85 | POLB (0.32) | POLBKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23905642 | 0.85 | POLB (0.30) | POLBKMT2AMAPT | |
| SCHEMBL23905608 | 0.83 | POLB (0.31) | POLBKMT2AMAPT | |
| SCHEMBL23905675 | 0.82 | PTGFR (0.32) | PTGFRPOLBKMT2ALMNATP53 | |
| SCHEMBL23904880 | 0.82 | PTGFR (0.33) | PTGFRPOLBMAPTLMNATP53 | |
| SCHEMBL23905889 | 0.82 | PTGFR (0.33) | PTGFRLMNATP53 | |
| SCHEMBL23905869 | 0.82 | GABRA5 (0.32) | PTGFRLMNATP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |