Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25116212 | 0.94 | IRAK4 (0.32) | IRAK4GABRA5HPGDSBACE1BACE2 | |
| SCHEMBL23904806 | 0.94 | IRAK4 (0.33) | IRAK4GABRA5HPGDSBACE1BACE2 | |
| SCHEMBL23905273 | 0.92 | LRRK2 (0.33) | IRAK4 | |
| SCHEMBL23905726 | 0.90 | BACE1 (0.32) | IRAK4GABRA5HPGDSBACE1GPR6 | |
| SCHEMBL24986796 | 0.88 | POLB (0.37) | GABRA5BACE1BACE2CFTR | |
| SCHEMBL25116292 | 0.88 | GPR6 (0.33) | IRAK4GPR6 | |
| SCHEMBL24985910 | 0.87 | CFTR (0.33) | GABRA5CFTR | |
| SCHEMBL24985908 | 0.87 | CFTR (0.33) | GABRA5CFTR | |
| SCHEMBL24986117 | 0.85 | GABRA5 (0.34) | GABRA5CFTR | |
| SCHEMBL24986121 | 0.85 | GABRA5 (0.34) | GABRA5CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |