Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MTTP | P55157 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905664 | 0.92 | MAPT (0.33) | ROCK2ROCK1MAPTRORCRAF1 | |
| SCHEMBL23905987 | 0.87 | — | — | |
| SCHEMBL23905668 | 0.86 | CFTR (0.34) | — | |
| SCHEMBL23905687 | 0.86 | CFTR (0.33) | MAPT | |
| SCHEMBL23905684 | 0.85 | THRB (0.34) | MAPT | |
| SCHEMBL23905991 | 0.85 | ROCK2 (0.32) | ROCK2ROCK1PROKR1MAPTMTTP | |
| SCHEMBL23905292 | 0.85 | — | — | |
| SCHEMBL23905347 | 0.85 | CFTR (0.32) | — | |
| SCHEMBL25113940 | 0.84 | CFTR (0.32) | — | |
| SCHEMBL23905573 | 0.83 | PPARD (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |