Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.46 |
| ▸ | RXRB | P28702 | 8/20 | 0.46 |
| ▸ | RXRG | P48443 | 6/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23882644 | 0.85 | MAOB (0.47) | HPGDALDH1A1MAPTLTB4RLTB4R2 | |
| SCHEMBL23905943 | 0.84 | GRM5 (0.41) | MRGPRX4HPGDALDH1A1LTB4RLTB4R2 | |
| SCHEMBL23882634 | 0.80 | MAOB (0.42) | MRGPRX4HPGDALDH1A1LTB4RLTB4R2 | |
| SCHEMBL32675527 | 0.80 | MAOB (0.42) | MRGPRX4HPGDALDH1A1LTB4RLTB4R2 | |
| SCHEMBL30251165 | 0.78 | LTB4R (0.36) | MRGPRX4MAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL30251516 | 0.78 | LTB4R (0.36) | MRGPRX4MAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL30251166 | 0.78 | LTB4R (0.36) | MRGPRX4MAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL23882847 | 0.78 | LTB4R (0.36) | MRGPRX4MAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL30251015 | 0.78 | LTB4R (0.36) | MRGPRX4MAPTLTB4RLTB4R2GRM5 | |
| SCHEMBL23905955 | 0.76 | GRM5 (0.60) | MRGPRX4HPGDALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |