Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | AHCY | P23526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714848 | 0.74 | NEK2 (0.39) | — | |
| SCHEMBL19730197 | 0.73 | KDM1A (0.40) | — | |
| SCHEMBL19730170 | 0.72 | ADCY5 (0.52) | — | |
| SCHEMBL14447403 | 0.70 | MEN1 (0.43) | ADORA2A | |
| SCHEMBL23966904 | 0.66 | GRM7 (0.34) | GRM1JAK2 | |
| SCHEMBL30180778 | 0.66 | GRM7 (0.34) | GRM1JAK2 | |
| SCHEMBL15448570 | 0.66 | TFPI2 (0.36) | GRM5DGAT1ALDH1A1TSHR | |
| SCHEMBL6704088 | 0.65 | DHFR (0.47) | ALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL15910562 | 0.63 | MEN1 (0.38) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL15448436 | 0.63 | DRD2 (0.36) | DGAT1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202480-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |