Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330035 | 0.85 | FPR2 (0.41) | KMT2AMEN1MGLLFPR2MAPT | |
| SCHEMBL23907026 | 0.83 | ALDH1A1 (0.40) | KMT2AMGLLLMNAADORA3FPR2 | |
| SCHEMBL4325939 | 0.81 | MAPT (0.51) | KMT2AMEN1LMNAADORA3MAPT | |
| SCHEMBL23907022 | 0.80 | MAPT (0.47) | KMT2AMEN1MGLLLMNAFPR2 | |
| SCHEMBL23907014 | 0.80 | KMT2A (0.52) | KMT2AMEN1MGLLLMNAADORA3 | |
| SCHEMBL23907032 | 0.79 | MAPT (0.45) | KMT2AMEN1MGLLLMNAADORA3 | |
| SCHEMBL23907024 | 0.78 | FPR2 (0.39) | FPR2MAPTNPBWR1MCHR1 | |
| SCHEMBL4339381 | 0.75 | BCHE (0.43) | KMT2AMEN1MGLLFPR2MAPT | |
| SCHEMBL23907037 | 0.74 | MAPT (0.34) | LMNAMAPT | |
| SCHEMBL4322549 | 0.72 | HSD11B1 (0.40) | KMT2AMEN1MGLLLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-B1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2024-08-28 | — | — | EP | disclosed |
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |