Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907008 | 0.87 | MAPT (0.49) | MAPTIDO1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL23907003 | 0.83 | MAPT (0.61) | MAPTIDO1TAAR1KMT2AGPR55 | |
| SCHEMBL23907005 | 0.81 | MAPT (0.48) | MAPTIDO1TAAR1LMNAHTT | |
| SCHEMBL23907037 | 0.79 | MAPT (0.34) | MAPTLMNA | |
| SCHEMBL23907020 | 0.79 | MAPT (0.54) | MAPTIDO1TAAR1KMT2AGPR55 | |
| SCHEMBL23907022 | 0.79 | MAPT (0.47) | MAPTIDO1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL23907021 | 0.78 | IDO1 (0.51) | MAPTIDO1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL23918516 | 0.73 | MAPT (0.48) | MAPTIDO1KMT2ALMNAMEN1 | |
| SCHEMBL23907013 | 0.72 | BCHE (0.39) | MAPTKMT2ALMNAMEN1HTT | |
| SCHEMBL23907010 | 0.71 | MAPT (0.46) | MAPTKMT2ALMNANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |