Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907008 | 0.85 | MAPT (0.49) | MAPTALDH1A1RAB9ASMN1; SMN2HTT | |
| SCHEMBL23907026 | 0.84 | ALDH1A1 (0.40) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL23907007 | 0.77 | ALDH1A1 (0.46) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL23907009 | 0.76 | MAPT (0.55) | MAPTALDH1A1LMNABCHEPTGS2 | |
| SCHEMBL4339501 | 0.72 | PTGS2 (0.48) | MAPTALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL23907005 | 0.72 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL4329727 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL23907003 | 0.71 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2HTTNPSR1 | |
| SCHEMBL23907019 | 0.71 | MAPT (0.44) | MAPTALDH1A1RAB9ASMN1; SMN2HTT | |
| SCHEMBL4325939 | 0.70 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-B1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2024-08-28 | — | — | EP | disclosed |
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |