Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907003 | 0.88 | MAPT (0.61) | MAPTSMN1; SMN2LMNAALDH1A1ALOX15 | |
| SCHEMBL23907020 | 0.81 | MAPT (0.54) | MAPTSMN1; SMN2LMNAALDH1A1ALOX15 | |
| SCHEMBL23907008 | 0.78 | MAPT (0.49) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL4326241 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAALDH1A1ALOX15BCHE | |
| SCHEMBL23907005 | 0.75 | MAPT (0.48) | MAPTSMN1; SMN2LMNAALDH1A1IDO1 | |
| SCHEMBL23907019 | 0.73 | MAPT (0.44) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL23907022 | 0.73 | MAPT (0.47) | MAPTSMN1; SMN2LMNAALDH1A1PTGS2 | |
| SCHEMBL23907021 | 0.72 | IDO1 (0.51) | MAPTLMNAALDH1A1ALOX15IDO1 | |
| SCHEMBL2449608 | 0.70 | ALOX15 (0.68) | MAPTSMN1; SMN2LMNAALDH1A1ALOX15 | |
| SCHEMBL13913866 | 0.69 | MAPT (0.53) | MAPTSMN1; SMN2LMNAALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |