Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 14/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907008 | 0.88 | MAPT (0.49) | MAPTIDO1HTTLMNASMN1; SMN2 | |
| SCHEMBL23907022 | 0.88 | MAPT (0.47) | MAPTIDO1HTTLMNASMN1; SMN2 | |
| SCHEMBL23907003 | 0.87 | MAPT (0.61) | MAPTIDO1HTTLMNASMN1; SMN2 | |
| SCHEMBL23907020 | 0.85 | MAPT (0.54) | MAPTIDO1HTTLMNASMN1; SMN2 | |
| SCHEMBL23907021 | 0.84 | IDO1 (0.51) | MAPTIDO1LMNAFPR2ALDH3A1 | |
| SCHEMBL23907019 | 0.81 | MAPT (0.44) | MAPTIDO1HTTLMNASMN1; SMN2 | |
| SCHEMBL4330035 | 0.79 | FPR2 (0.41) | MAPTSMN1; SMN2FPR2ALDH1A1CYP1A2 | |
| SCHEMBL23918516 | 0.75 | MAPT (0.48) | MAPTIDO1HTTLMNASMN1; SMN2 | |
| SCHEMBL23907010 | 0.72 | MAPT (0.46) | MAPTHTTLMNASMN1; SMN2FPR2 | |
| SCHEMBL23907025 | 0.71 | GAA (0.48) | MAPTLMNASMN1; SMN2FPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |