Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.33 |
| ▸ | AOC2 | O75106 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907231 | 1.00 | L3MBTL1 (0.49) | L3MBTL1PLA2G4AALKBH2HPGDSACHE | |
| SCHEMBL23920660 | 0.87 | L3MBTL1 (0.38) | L3MBTL1ACHEAOC3MAOB | |
| SCHEMBL22216433 | 0.85 | L3MBTL1 (0.56) | L3MBTL1PLA2G4AALKBH2HPGDSACHE | |
| SCHEMBL22216184 | 0.85 | L3MBTL1 (0.36) | L3MBTL1ACHEAOC3AOC2MAOB | |
| SCHEMBL22206967 | 0.83 | GRM2 (0.38) | L3MBTL1ACHEAOC3MAOB | |
| SCHEMBL22216335 | 0.83 | KLKB1 (0.37) | L3MBTL1ACHEAOC3MAOB | |
| SCHEMBL22206966 | 0.83 | GRM2 (0.38) | L3MBTL1ACHEAOC3MAOB | |
| SCHEMBL22216339 | 0.81 | KLKB1 (0.41) | L3MBTL1 | |
| SCHEMBL22216213 | 0.81 | KLKB1 (0.43) | AOC3AOC2MAOB | |
| SCHEMBL22216259 | 0.81 | LMNA (0.45) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892621-A1 | HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |