Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907231 | 0.85 | L3MBTL1 (0.49) | L3MBTL1PLA2G4AACHEALKBH2HPGDS | |
| SCHEMBL23907233 | 0.85 | L3MBTL1 (0.49) | L3MBTL1PLA2G4AACHEALKBH2HPGDS | |
| SCHEMBL22216435 | 0.85 | L3MBTL1 (0.39) | L3MBTL1ACHECCNCCDK8LMNA | |
| SCHEMBL23920716 | 0.85 | HPGD (0.40) | L3MBTL1PLA2G4AACHELMNAMAPT | |
| SCHEMBL22216455 | 0.83 | LMNA (0.42) | L3MBTL1ACHELMNAMAPTCYP2C19 | |
| SCHEMBL22216190 | 0.82 | AOC3 (0.42) | L3MBTL1ACHELMNAMAPTCYP2C19 | |
| SCHEMBL23907175 | 0.77 | KMT2A (0.45) | L3MBTL1ALKBH2HPGDSEGLN1MAPT | |
| SCHEMBL23907174 | 0.77 | KMT2A (0.45) | L3MBTL1ALKBH2HPGDSEGLN1MAPT | |
| SCHEMBL22216318 | 0.77 | LMNA (0.51) | L3MBTL1LMNAMAPTCYP2C19GFER | |
| SCHEMBL23907153 | 0.77 | L3MBTL1 (0.41) | L3MBTL1PLA2G4AACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892621-A1 | HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020143763-A1 | HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF | 南京药捷安康生物科技有限公司 | 2020-07-16 | — | — | WO | disclosed |