Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820793 | 0.83 | TDP1 (0.70) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL9242177 | 0.80 | PTGDR2 (0.43) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL28328185 | 0.77 | TDP1 (0.73) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL21820773 | 0.76 | TDP1 (0.46) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| Chlorpyrifos SCHEMBL28307061 | 0.75 | TDP1 (0.69) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL23909385 | 0.74 | TDP1 (0.47) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL13196459 | 0.73 | TDP1 (0.52) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL21820799 | 0.71 | TDP1 (0.56) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL634976 | 0.71 | TDP1 (0.64) | TDP1CYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL23909395 | 0.68 | TDP1 (0.40) | TDP1CYP3A4TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |