Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820799 | 0.91 | TDP1 (0.56) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL23909385 | 0.82 | TDP1 (0.47) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL21820793 | 0.78 | TDP1 (0.70) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| Chlorpyrifos SCHEMBL28307061 | 0.78 | TDP1 (0.69) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL21820773 | 0.74 | TDP1 (0.46) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL23909401 | 0.73 | TDP1 (0.48) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL28328185 | 0.70 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| Chlorpyrifos SCHEMBL7908295 | 0.70 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| Chlorpyrifos SCHEMBL21680 | 0.70 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL23909395 | 0.69 | TDP1 (0.40) | TDP1MAPK1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389296-B2 | Assay devices and methods and components for use therein | SELECTIVE ANTIBODIES LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-8389296-B2 | Assay devices and methods and components for use therein | SELECTIVE ANTIBODIES LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-20100209295-A1 | ASSAY DEVICES AND METHODS AND COMPONENTS FOR USE THEREIN | SELECTIVE ANTIBODIES LIMITED (GB) | 2010-08-19 | — | — | US | disclosed |
| US-20100209295-A1 | ASSAY DEVICES AND METHODS AND COMPONENTS FOR USE THEREIN | SELECTIVE ANTIBODIES LIMITED (GB) | 2010-08-19 | — | — | US | disclosed |