Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909385 | 0.83 | TDP1 (0.47) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL21820773 | 0.82 | TDP1 (0.46) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL21820799 | 0.77 | TDP1 (0.56) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL990015 | 0.73 | TDP1 (0.51) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL13196459 | 0.69 | TDP1 (0.52) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL16506502 | 0.69 | TDP1 (0.54) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9242177 | 0.69 | PTGDR2 (0.43) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL23909401 | 0.68 | TDP1 (0.48) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| Triclopyr SCHEMBL29007141 | 0.68 | KDM4E (0.41) | TDP1ALDH1A1CYP3A4MAPTALOX15 | |
| Triclopyr SCHEMBL149659 | 0.67 | TDP1 (0.45) | TDP1ALDH1A1CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172981-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) | 2023-06-08 | — | — | US | disclosed |
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |