Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 15/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23910122 | 0.84 | KDM4E (0.50) | KDM4ELMNAGAAMAPTHSD17B10 | |
| SCHEMBL23909980 | 0.81 | ALDH1A1 (0.49) | LMNAGAAMAPTARALDH1A1 | |
| SCHEMBL21072066 | 0.76 | KDM4E (0.50) | KDM4ELMNAGAAMAPTHSD17B10 | |
| SCHEMBL25011674 | 0.72 | GAA (0.41) | KDM4EGAAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL23910094 | 0.71 | — | — | |
| SCHEMBL20265273 | 0.69 | KDM4E (0.55) | KDM4ELMNAGAAMAPTHSD17B10 | |
| SCHEMBL964746 | 0.67 | KDM4E (0.49) | KDM4ELMNAGAAMAPTHSD17B10 | |
| SCHEMBL30506365 | 0.67 | TYK2 (0.40) | ARJAK2 | |
| SCHEMBL7319585 | 0.67 | KDM4E (0.48) | KDM4ELMNAGAAMAPTHSD17B10 | |
| SCHEMBL1842982 | 0.66 | KDM4E (0.51) | KDM4ELMNAGAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | KDM4E 4547/4885LMNA 2967/4885GAA 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.