Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.61 |
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28237282 | 1.00 | TSHR (0.63) | TSHRTP53HTTPLA2G4BRARB | |
| SCHEMBL27852060 | 0.92 | TSHR (0.60) | TSHRTP53HTTPLA2G4BRARB | |
| Terephthalic Acid SCHEMBL28336967 | 0.89 | TP53 (0.63) | TSHRTP53HTTPLA2G4BRARB | |
| Cetyl Palmitate SCHEMBL8430810 | 0.87 | TSHR (0.60) | TSHRTP53HTTPLA2G4BRARB | |
| Benzoic Acid SCHEMBL27584260 | 0.86 | TSHR (0.59) | TSHRTP53HTTPLA2G4BRARB | |
| SCHEMBL8775319 | 0.86 | RARB (0.59) | TSHRTP53PLA2G4BRARBDGKA | |
| SCHEMBL15286485 | 0.85 | TP53 (0.57) | TSHRTP53HTTPLA2G4BRARB | |
| Terephthalic Acid SCHEMBL17504571 | 0.84 | TP53 (0.65) | TSHRTP53HTTPLA2G4BRARB | |
| SCHEMBL12971158 | 0.83 | RAB9A (0.64) | TSHRDGKALMNAESR1CYP1A2 | |
| SCHEMBL43342 | 0.83 | DGKA (0.78) | TSHRDGKALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110396283-A | A kind of biodegradable articles and preparation method thereof | SHANGHAI CHANGFA NEW MAT CO LTD | 2019-11-01 | — | — | CN | claimed |
| CN-110256824-A | Calcium lignin composite completely biodegradable film and preparation method thereof | 南京工业大学 | 2019-09-20 | — | — | CN | claimed |
| CN-110003638-A | A kind of calcium carbonate height filling Biodegradable film and preparation method thereof | 福建师范大学泉港石化研究院 | 2019-07-12 | — | — | CN | claimed |
| CN-106832801-B | A kind of lignin modification PBAT biodegradable plastic and preparation method thereof | 济宁明升新材料有限公司 | 2019-07-02 | — | — | CN | claimed |
| CN-109694556-A | A kind of biodegradable master batch for agricultural film of weeding and preparation method thereof | 上海昶法新材料有限公司 | 2019-04-30 | — | — | CN | claimed |
| CN-108948679-A | A kind of lignin modification starch base PBAT biodegrade membrane material and preparation method thereof | 济宁明升新材料有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-108485207-A | Fully-degradable mulching film with phosphate fertilizer slow-release effect and preparation method thereof | 南京工业大学 | 2018-09-04 | — | — | CN | claimed |
| CN-108359224-A | Fully-degradable mulching film with effect of slowly releasing nitrogen fertilizer and preparation method thereof | 南京工业大学 | 2018-08-03 | — | — | CN | claimed |
| CN-106832801-A | A kind of lignin modification PBAT biodegradable plastics and preparation method thereof | 济宁明升新材料有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-102492248-B | Large molecular nucleating agent for poly butylenes succinate and copolyester of poly butylenes succinate and application thereof | UNIV BEIJING TECH & BUSINESS | 2014-04-16 | — | — | CN | claimed |
| CN-102492248-A | Large molecular nucleating agent for poly butylenes succinate and copolyester of poly butylenes succinate and application thereof | UNIV BEIJING TECH & BUSINESS | 2012-06-13 | — | — | CN | claimed |
| CN-118339235-A | Marine biodegradation accelerator having hydrocarbon group and marine biodegradable composition | 日清纺控股株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-118317993-A | Marine biodegradable polymer compound, marine biodegradation accelerator, and marine biodegradable resin composition | 日清纺控股株式会社 | 2024-07-09 | — | — | CN | disclosed |
| CN-118302489-A | Marine biodegradation accelerator having two or more monovalent organic anions, and marine biodegradable composition | 日清纺控股株式会社 | 2024-07-05 | — | — | CN | disclosed |
| CN-118284641-A | Marine biodegradable polyol, marine biodegradable polymer compound, and marine biodegradable resin composition | 日清纺控股株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-102492248-A | Large molecular nucleating agent for poly butylenes succinate and copolyester of poly butylenes succinate and application thereof | UNIV BEIJING TECH & BUSINESS | 2012-06-13 | — | — | CN | disclosed |
| CN-101511944-B | Thermoplastic resin composition and molded article thereof | TORAY INDUSTRIES | 2011-08-24 | — | — | CN | disclosed |
| CN-101511944-A | Thermoplastic resin composition and molded article thereof | TORAY INDUSTRIES (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-100425636-C | Polyalkylene terephthalate and process for producing the same | ASAHI CHEMICAL CORP (JP) | 2008-10-15 | — | — | CN | disclosed |
| CN-1867606-A | Process for producing polyalkylene terephthalate, process for producing polyalkylene terephthalate molding and polyalkylene terephthalate molding | ASAHI CHEMICAL CORP (JP) | 2006-11-22 | — | — | CN | disclosed |