Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686762 | 0.79 | LRRK2 (0.50) | MEN1KMT2AHTR7LRRK2ALDH1A1 | |
| SCHEMBL15205661 | 0.79 | ATM (0.43) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL4035843 | 0.78 | CYP2C19 (0.50) | ALDH1A1KDM4EDRD2ADRA1ACYP1A2 | |
| SCHEMBL17614048 | 0.76 | HTR7 (0.36) | MEN1KMT2AHTR7LRRK2ALDH1A1 | |
| SCHEMBL4647621 | 0.75 | CYP1A2 (0.38) | HTR7ALDH1A1HRH4ADRA1DHTR2C | |
| SCHEMBL2523541 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL22385034 | 0.75 | RIOK2 (0.32) | MEN1KMT2AALDH1A1KDM4ERIOK2 | |
| SCHEMBL2170006 | 0.74 | CCNC (0.47) | MEN1KMT2AALDH1A1KDM4EHRH4 | |
| SCHEMBL28978598 | 0.74 | HTR7 (0.36) | HTR7LRRK2ALDH1A1DRD2ADRA1D | |
| SCHEMBL26686538 | 0.74 | SMN1; SMN2 (0.44) | MEN1KMT2AHTR7LRRK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916778-A | Methionine adenosyltransferase inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2022053022-A1 | METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 赛诺哈勃药业（成都）有限公司 | 2022-03-17 | — | — | WO | disclosed |
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | USP7, SENP7, USP8 | MEN1 3693/4885KMT2A 2614/4885HTR7 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.