Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.54 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242802 | 1.00 | PTGS2 (0.54) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL10276277 | 1.00 | PTGS2 (0.54) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL27697908 | 0.88 | PTGS1 (0.40) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL9425565 | 0.84 | PTGS2 (0.56) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL3674499 | 0.84 | PTGS2 (0.69) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL66534 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL2319534 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL1345158 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL29393183 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL6903957 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1CXCR1CXCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776300-A | The synthetic method of loxoprofen sodium | 浙江大学 | 2019-05-21 | — | — | CN | claimed |
| CN-105461678-B | A kind of new process synthesizing 2- (4 ' -2-bromomethylphenyl) propionic acid intermediate ketal | 武汉工程大学 | 2019-01-18 | — | — | CN | claimed |
| CN-109180464-A | Gas circulation method prepares 2- (4- 2-bromomethylphenyl) propionic acid | 浙江大学 | 2019-01-11 | — | — | CN | claimed |
| CN-109180470-A | Liquid phase circulation method prepares 2- (4- 2-bromomethylphenyl) propionic acid | 浙江大学 | 2019-01-11 | — | — | CN | claimed |
| CN-108586233-A | The method for synthesizing 2- (4 ' -2-bromomethylphenyl) propionic ester | 湖北迅达药业股份有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-107473960-A | Pipelineization prepares the method and its device of 2 (4 2-bromomethylphenyl) propionic acid | 浙江工业大学 | 2017-12-15 | — | — | CN | claimed |
| CN-105214692-B | Supported solid catalyst and preparation method thereof and its application | 湖北迅达药业股份有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-105131035-B | Amino group compound and sugar chain labeled mass spectrum derivatization reagent with positive charges | 延边大学 | 2017-03-22 | — | — | CN | claimed |
| CN-104744237-B | A kind of 2-(4-2-bromomethylphenyl) propanoic acid preparation method | 浙江博聚新材料有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-105218351-A | A kind of synthetic method of loxoprofen sodium | SHANGHAI RECORDCHEM TECHNOLOGY CO LTD | 2016-01-06 | — | — | CN | claimed |
| CN-105017009-A | Loxoprofen sodium synthesis method | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-11-04 | — | — | CN | claimed |
| CN-104744237-A | Preparation method of 2-(4-bromomethylphenyl) propionic acid | LISHUI NANMING CHEMICAL CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-103265426-B | Environment-friendly preparation method of 2 - (4 - Bromomethylphenyl) propionic acid based on two-phase free radical reaction | FUJIAN SANTAI BIOLOG PHARMACY CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-104447284-A | Synthetic method of 2-(4-bromomethyl phenyl) propionic acid | CHEER FINE PHARMACEUTICAL ANHUI CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-103265426-A | Environment-friendly preparation method of 2 - (4 - Bromomethylphenyl) propionic acid based on two-phase free radical reaction | FUJIAN SANTAI BIOLOG PHARMACY CO LTD | 2013-08-28 | — | — | CN | claimed |
| CN-101412670-B | Method for synthesizing loxoprofen sodium | ZHEJIANG APELOA PHARMACEUTICAL SCIENCE & TECHNOLOGY CO LTD | 2011-11-09 | — | — | CN | claimed |
| CN-101412670-A | Method for synthesizing loxoprofen sodium | ZHEJIANG PULUO PHARMACEUTICAL (CN) | 2009-04-22 | — | — | CN | claimed |
| CN-101062892-A | Synthesis of 2-(4-Bromomethylphenyl) ethylformic acid | HANGZHOU PENTATOMIC SCIENCE & (CN) | 2007-10-31 | — | — | CN | claimed |
| CN-1101802-C | Process for preparing loxoprofen sodium | UNIV FUDAN (CN) | 2003-02-19 | — | — | CN | claimed |
| CN-1294115-A | Process for preparing loxoprofen sodium | UNIV FUDAN (CN) | 2001-05-09 | — | — | CN | claimed |