Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.64 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.64 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | RARB | P10826 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393183 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL66533 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL1345158 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL4264095 | 0.88 | TAAR1 (0.53) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL15295486 | 0.88 | TAAR1 (0.53) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL15295485 | 0.88 | TAAR1 (0.53) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL9015267 | 0.85 | LMNA (0.50) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL9425565 | 0.84 | PTGS2 (0.56) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL3674499 | 0.84 | PTGS2 (0.69) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL4943395 | 0.83 | PTGS2 (0.51) | PTGS2PTGS1CXCR1CXCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116046948-A | Related substance analysis method of compound preparation ibuprofen renin tablet | 南京工业大学 | 2023-05-02 | — | — | CN | claimed |
| CN-102716069-A | Injection liquid containing ibuprofen and preparation process of injection liquid | WUXI KFT PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-10-10 | — | — | CN | claimed |
| US-12551420-B2 | 1-alkoxyethyl-3-isobutyl-benzene and 1-carboxyethyl-3-isobutyl-benzene as aroma ingredients | BASF SE (DE) | 2026-02-17 | — | — | US | disclosed |
| CN-115955956-B | 1-Alkoxyethyl-3-isobutylbenzene and 1-carboxyethyl-3-isobutylbenzene as aromatic components | 巴斯夫欧洲公司 | 2026-01-13 | — | — | CN | disclosed |
| US-20240024213-A1 | 1-ALKOXYETHYL-3-ISOBUTYL-BENZENE AND 1-CARBOXYETHYL-3-ISOBUTYL-BENZENE AS AROMA INGREDIENTS | BASF SE (DE) | 2024-01-25 | — | — | US | disclosed |
| EP-4225727-A1 | 1-ALKOXYETHYL-3-ISOBUTYL-BENZENE AND 1-CARBOXYETHYL-3-ISOBUTYL-BENZENE AS AROMA INGREDIENTS | BASF SE (DE) | 2023-08-16 | — | — | EP | disclosed |
| EP-4225727-A1 | 1-ALKOXYETHYL-3-ISOBUTYL-BENZENE AND 1-CARBOXYETHYL-3-ISOBUTYL-BENZENE AS AROMA INGREDIENTS | BASF SE (DE) | 2023-08-16 | — | — | EP | disclosed |
| EP-3978469-B1 | 1-ALKOXYETHYL-3-ISOBUTYL-BENZENE AND 1-CARBOXYETHYL-3-ISOBUTYL-BENZENE AS AROMA INGREDIENTS | BASF SE (DE) | 2023-07-26 | — | — | EP | disclosed |
| CN-114062554-B | Analysis method for simultaneously measuring related substances of acetaminophen ibuprofen | 山东百诺医药股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116046948-A | Related substance analysis method of compound preparation ibuprofen renin tablet | 南京工业大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-115955956-A | 1-alkoxyethyl-3-isobutylbenzene and 1-carboxyethyl-3-isobutylbenzene as aromatic components | 巴斯夫欧洲公司 | 2023-04-11 | — | — | CN | disclosed |
| EP-1638505-A2 | AMPHIPHILIC PYRIDINIUM COMPOUNDS, METHOD OF MAKING AND USE THEREOF | HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005002519-A2 | AMPHIPHILIC PYRIDINIUM COMPOUNDS, METHOD OF MAKING AND USE THEREOF | HENRY M.JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| EP-0474509-B1 | Method for purification of ibuprofen comprising mixtures | HOECHST CELANESE CORP (US) | 1997-03-12 | — | — | EP | disclosed |
| CN-1025609-C | Process for purifying 2-(4-isobutylphenyl)-propionic acid | HOECHST AG (US) | 1994-08-10 | — | — | CN | disclosed |
| EP-0326027-B1 | PROCESS FOR THE PURIFICATION OF 2-(4-ISOBUTYLPHENYL)-PROPIONIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | EP | disclosed |
| US-5151551-A | Heating, washing with water, azeotroping, destabilization and crystallization | HOECHST CELANESE CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| EP-0474509-A2 | Method for purification of ibuprofen comprising mixtures | HOECHST CELANESE CORPORATION (US) | 1992-03-11 | — | — | EP | disclosed |
| CN-1035821-A | The method of purification of 2-(4-isobutylphenyl)-propionic acid | HOECHST AG (DE) | 1989-09-27 | — | — | CN | disclosed |
| EP-0326027-A1 | Process for the purification of 2-(4-isobutylphenyl)-propionic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12551420-B2 | 1-alkoxyethyl-3-isobutyl-benzene and 1-carboxyethyl-3-isobutyl-benzene as aroma ingredients | EBP, OR10J3, ADRA1D | PTGS2 1189/4885PTGS1 698/4885CXCR1 340/4885 |
| US-20240024213-A1 | 1-ALKOXYETHYL-3-ISOBUTYL-BENZENE AND 1-CARBOXYETHYL-3-ISOBUTYL-BENZENE AS AROMA INGREDIENTS | CYP1B1, ALKBH1, ALKBH3 | PTGS2 2135/4885PTGS1 1306/4885CXCR1 595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.