SCHEMBL23910875

SCHEMBL23910875

CO/C=C/c1cc2c(Cl)ccnc2n1S(=O)(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 11/20 0.39
ENPP3 O14638 2/20 0.39
ENPP1 P22413 2/20 0.39
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SRC P12931 1/20 0.35
NFE2L2 Q16236 2/20 0.35
CYP2C19 P33261 1/20 0.33
DCTPP1 Q9H773 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23910877 1.00 PTGDR2 (0.39) PTGDR2ENPP3ENPP1KDM4EALDH1A1
SCHEMBL20765258 0.83 ENPP3 (0.43) PTGDR2ENPP3ENPP1KDM4EALDH1A1
SCHEMBL18376651 0.82 SRC (0.35) KDM4EALDH1A1GAAPKMHTT
SCHEMBL1154907 0.80 PTGDR2 (0.48) PTGDR2ENPP3ENPP1KDM4EALDH1A1
SCHEMBL29959159 0.80 PTGDR2 (0.48) PTGDR2ENPP3ENPP1KDM4EALDH1A1
SCHEMBL5661951 0.76 ENPP3 (0.44) PTGDR2ENPP3ENPP1KDM4EALDH1A1
SCHEMBL30751165 0.76 ENPP3 (0.44) PTGDR2ENPP3ENPP1KDM4EALDH1A1
SCHEMBL25324645 0.76 ENPP3 (0.44) PTGDR2ENPP3ENPP1KDM4EALDH1A1
SCHEMBL18980291 0.75 PIK3C3 (0.46) PTGDR2ENPP3ENPP1KDM4EALDH1A1
SCHEMBL16546218 0.75 PTGDR2 (0.45) PTGDR2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF USP7, SENP7, USP8 PTGDR2 4346/4885ENPP3 1611/4885ENPP1 1543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.