Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676043 | 1.00 | MEN1 (0.77) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL935186 | 0.87 | MEN1 (1.00) | MEN1KMT2ANR1H4MAPTLMNA | |
| Benzene SCHEMBL27988126 | 0.87 | MEN1 (1.00) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL1680043 | 0.86 | KMT2A (0.58) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL1675511 | 0.85 | KMT2A (0.57) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL1674862 | 0.84 | MEN1 (0.56) | MEN1KMT2ANR1H4MAPTLMNA | |
| Butane SCHEMBL6828046 | 0.84 | MEN1 (0.93) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL27655716 | 0.84 | MEN1 (0.74) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL321699 | 0.84 | MEN1 (0.74) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL321698 | 0.84 | MEN1 (0.74) | MEN1KMT2ANR1H4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117694403-A | Dendrobium devonianum extract and application thereof in preparation of anti-alcohol preparation | 湖北省医药工业研究院有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-114702384-B | Method for preparing p-hydroxy cinnamic acid ester by catalyzing alcoholysis of lignin through enzymolysis lignin-based hierarchical porous carbon loaded molybdenum oxide | 华南理工大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-114702384-A | Method for preparing p-hydroxycinnamate by catalyzing alcoholysis of lignin through enzymatic hydrolysis of lignin-based hierarchical porous carbon-supported molybdenum oxide | 华南理工大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-109303772-B | Application of p-hydroxy ethyl cinnamate | 集美大学 | 2021-12-24 | — | — | CN | disclosed |
| CN-108911985-B | Method for separating and purifying ethyl p-hydroxycinnamate from camellia pollen and application of ethyl p-hydroxycinnamate | 集美大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-104204120-B | Cured film formation composition, oriented material and phase difference material | 日产化学工业株式会社 | 2017-03-08 | — | — | CN | disclosed |
| CN-103965048-A | Trans cinnamic acid ester compound, as well as synthetic method and application thereof | UNIV NORTHWEST A&F | 2014-08-06 | — | — | CN | disclosed |
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |
| US-7407691-B2 | Photopolymerizable oxetane derivative and liquid-crystal composition containing it | CHISSO CORPORATION (JP) | 2008-08-05 | — | — | US | disclosed |
| CN-100348569-C | Induction of apoptosis in cancer cells | BURNHAM INST (US) | 2007-11-14 | — | — | CN | disclosed |
| US-7053071-B2 | For therapy of leukemia or other forms of cancer or for treating disease conditions caused by apoptosis of cells | THE BURNHAM INSTITUTE (US) | 2006-05-30 | — | — | US | disclosed |
| US-20050224757-A1 | Photopolymerizable oxetane derivative and liquid-crystal composition containing it | JNC PETROCHEMICAL CORPORATION (JP) | 2005-10-13 | — | — | US | disclosed |
| CN-1659130-A | Induction of apoptosis in cancer cells | BURNHAM INST (US) | 2005-08-24 | — | — | CN | disclosed |
| EP-1456165-A1 | INDUCTION OF APOPTOSIS IN CANCER CELLS | The Burnham Institute (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20030176506-A1 | Induction of apoptosis in cancer cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH | 2003-09-18 | — | — | US | disclosed |
| WO-2003048101-A1 | INDUCTION OF APOPTOSIS IN CANCER CELLS | THE BURNHAM INSTITUTE (US) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050224757-A1 | Photopolymerizable oxetane derivative and liquid-crystal composition containing it | TAC3, CPNE4, CNPY3 | MEN1 4203/4885KMT2A 3807/4885NR1H4 2146/4885 |
| US-20030176506-A1 | Induction of apoptosis in cancer cells | MCL1, BAD, BCL2 | MEN1 4445/4885KMT2A 3080/4885NR1H4 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.