Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23911242 | 0.86 | USP7 (0.47) | LMNAMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL23911123 | 0.84 | GRIN3B (0.39) | MEN1KMT2APOLBGRIN3BGRIN1 | |
| SCHEMBL23911584 | 0.84 | MTNR1A (0.40) | MEN1KMT2AL3MBTL1POLBGRIN3B | |
| SCHEMBL25298145 | 0.78 | AKT2 (0.41) | GRIN3BGRIN1GRIN2CUSP7GRIN2D | |
| SCHEMBL23910822 | 0.76 | GRIN3B (0.32) | GRIN3BGRIN1GRIN2CGRIN2DGRIN2A | |
| SCHEMBL26916157 | 0.76 | GRIN3B (0.39) | MEN1KMT2AL3MBTL1GRIN3BGRIN1 | |
| SCHEMBL23911601 | 0.75 | MALT1 (0.36) | POLBUSP7 | |
| SCHEMBL23911555 | 0.75 | CYP2C9 (0.32) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL1850156 | 0.73 | USP7 (0.40) | GRIN3BGRIN1GRIN2CUSP7TYK2 | |
| SCHEMBL26917014 | 0.73 | PYGL (0.37) | KMT2AGRIN3BGRIN1GRIN2CGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | USP7, SENP7, USP8 | LMNA 2421/4885PTGES 3278/4885MEN1 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.