Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.32 |
| ▸ | TYK2 | P29597 | 5/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.30 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23911061 | 1.00 | KDM5B (0.36) | KDM5BPIK3R1PIK3CAKDM4AKDM5A | |
| SCHEMBL23911060 | 1.00 | KDM5B (0.36) | KDM5BPIK3R1PIK3CAKDM4AKDM5A | |
| SCHEMBL13166681 | 0.83 | MET (0.36) | KDM5BPIK3R1PIK3CAKDM4AKDM5A | |
| SCHEMBL23911035 | 0.83 | AKT3 (0.33) | KDM4AKDM5AGRIN3BGRIN1GRIN2C | |
| SCHEMBL23911194 | 0.78 | L3MBTL1 (0.36) | KDM4AKDM5AGRIN3BGRIN1GRIN2C | |
| SCHEMBL22245555 | 0.78 | NPC1 (0.42) | PIK3R1PIK3CANPC1RAB9A | |
| SCHEMBL20973616 | 0.78 | NPC1 (0.42) | PIK3R1PIK3CANPC1RAB9A | |
| SCHEMBL27219071 | 0.77 | PSMB8 (0.35) | KDM4AKDM5A | |
| SCHEMBL32683432 | 0.76 | KDM4A (0.32) | KDM4AKDM5AGRIN3BGRIN1GRIN2C | |
| SCHEMBL20973662 | 0.74 | USP7 (0.33) | KDM4AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | USP7, SENP7, USP8 | KDM5B 1511/4885PIK3R1 2303/4885PIK3CA 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.