Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 5/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 3/20 | 0.40 |
| ▸ | WDR5 | P61964 | 3/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852493 | 0.81 | ADORA1 (0.50) | MPLMYCWDR5NPY5RCHEK1 | |
| SCHEMBL30309296 | 0.81 | ADORA1 (0.50) | MPLMYCWDR5NPY5RCHEK1 | |
| SCHEMBL30309335 | 0.78 | MYC (0.63) | MYCWDR5MEN1KMT2ANPY5R | |
| SCHEMBL1850689 | 0.78 | MYC (0.63) | MYCWDR5MEN1KMT2ANPY5R | |
| SCHEMBL29932816 | 0.78 | MPL (0.55) | MPLDPP4CDC7CCNE1CDK2 | |
| SCHEMBL23364821 | 0.78 | MPL (0.55) | MPLDPP4CDC7CCNE1CDK2 | |
| SCHEMBL22331561 | 0.74 | ADORA1 (0.53) | MEN1KMT2A | |
| SCHEMBL1449744 | 0.73 | CDC7 (0.58) | CDC7DBF4 | |
| SCHEMBL2488956 | 0.73 | CDC7 (0.64) | MPLCDC7CCNE1CDK2DBF4 | |
| SCHEMBL1853775 | 0.72 | RORB (0.52) | MPLMYCWDR5CTSKRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317112-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER AG (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317112-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER AG (DE) | 2021-10-14 | — | — | US | disclosed |
| CN-111601802-A | Heterocyclic compounds as pesticides | 拜耳股份有限公司 | 2020-08-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317112-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | MPL 4424/4885AR 3270/4885DPP4 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.