Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815173 | 0.90 | ROCK2 (0.40) | ROCK2TSHRSMN1; SMN2SLC5A1LMNA | |
| SCHEMBL20043922 | 0.84 | ROCK2 (0.39) | ROCK2SLC5A1CFDNOTUMMGLL | |
| SCHEMBL18815794 | 0.83 | ROCK2 (0.43) | ROCK2SLC5A1LMNAALDH1A1NPSR1 | |
| SCHEMBL20043920 | 0.81 | KMT2A (0.42) | ROCK2TSHRCFDTDP1MEN1 | |
| SCHEMBL23642604 | 0.81 | TRPM8 (0.48) | TSHRSMN1; SMN2LMNAALDH1A1EPHX2 | |
| SCHEMBL20043921 | 0.80 | ROCK2 (0.39) | ROCK2SMN1; SMN2SLC5A1ALDH1A1CFD | |
| SCHEMBL20043923 | 0.80 | HSD17B10 (0.39) | ROCK2SMN1; SMN2LMNAALDH1A1CFD | |
| SCHEMBL26163607 | 0.79 | TDP1 (0.49) | TSHRSMN1; SMN2LMNAALDH1A1NPSR1 | |
| SCHEMBL23642606 | 0.79 | TP53 (0.46) | TSHRSMN1; SMN2LMNAALDH1A1EPHX2 | |
| SCHEMBL18815175 | 0.79 | NPSR1 (0.41) | ROCK2TSHRSMN1; SMN2ALDH1A1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601263-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-10-13 | — | — | EP | disclosed |