Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815173 | 0.90 | ROCK2 (0.40) | TDP1NPSR1ALDH1A1USP2RAB9A | |
| SCHEMBL20044413 | 0.89 | MEN1 (0.47) | TDP1NPSR1ALDH1A1USP2RAB9A | |
| SCHEMBL20044140 | 0.87 | LMNA (0.52) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL20044027 | 0.86 | KMT2A (0.42) | NPSR1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20044383 | 0.85 | MEN1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL20043908 | 0.85 | MEN1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL20044415 | 0.83 | TP53 (0.41) | TDP1NPSR1ALDH1A1USP2RAB9A | |
| SCHEMBL20043989 | 0.83 | ALDH1A1 (0.43) | TDP1NPSR1ALDH1A1USP2RAB9A | |
| SCHEMBL20044170 | 0.83 | ALDH1A1 (0.43) | TDP1NPSR1ALDH1A1USP2RAB9A | |
| SCHEMBL20043922 | 0.83 | ROCK2 (0.39) | FPR2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278972-A1 | SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES | FMC CORPORATION | 2023-09-07 | — | — | US | disclosed |
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278972-A1 | SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES | CBR3, CBR1, GRHPR | TDP1 1861/4885NPSR1 68/4885ALDH1A1 1354/4885 |
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | CYP1B1, CHRM2, CYP1A1 | TDP1 531/4885NPSR1 1644/4885ALDH1A1 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.