SCHEMBL23912050

SCHEMBL23912050

Cc1cccc(-c2ccc3c4ccccc4n(-c4cc(-c5cccnc5-c5ccccc5-c5ccccc5)cc(-n5c6ccccc6c6ccc(-c7cccc(C)c7)cc65)c4C#N)c3c2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.36
ADORA1 P30542 2/20 0.36
KDM4A O75164 1/20 0.35
KDM5B Q9UGL1 1/20 0.35
SQOR Q9Y6N5 2/20 0.34
ELANE P08246 2/20 0.33
PIP4K2A P48426 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
PPARG P37231 1/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
CYP11B2 P19099 1/20 0.32
LMNA P02545 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23912049 0.97 ADORA2A (0.38) ADORA2AADORA1KDM4AKDM5BSQOR
SCHEMBL23912045 0.94 ADORA2A (0.36) ADORA2AADORA1KDM4AKDM5BSQOR
SCHEMBL20619417 0.94 ADORA1 (0.37) ADORA2AADORA1KDM4AKDM5BSQOR
SCHEMBL20619419 0.92 ADORA1 (0.39) ADORA2AADORA1KDM4AKDM5BELANE
SCHEMBL23912019 0.90 ALDH1A1 (0.33) KDM5BSQORKDM4EHPGDCYP11B2
SCHEMBL23912068 0.90 ALDH1A1 (0.37) ADORA2AADORA1KDM4AKDM5BSQOR
SCHEMBL20619413 0.89 ADORA1 (0.37) ADORA2AADORA1KDM4AKDM5BSQOR
SCHEMBL20620051 0.87 CYP11B2 (0.33) ADORA2AADORA1SQORELANEKDM4E
SCHEMBL23912035 0.87 ALDH1A1 (0.35) ADORA2AADORA1SQORKDM4EHPGD
SCHEMBL20619690 0.87 ADORA1 (0.36) ADORA2AADORA1SQORKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645522-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-13 EP disclosed