SCHEMBL23912045

SCHEMBL23912045

Cc1cccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3cccnc3-c3ccccc3-c3ccccc3)cc(-n3c4ccccc4c4cc(-c5cccc(C)c5)ccc43)c2C#N)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.36
ADORA1 P30542 2/20 0.36
SQOR Q9Y6N5 2/20 0.34
ELANE P08246 2/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
PPARG P37231 1/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
CYP11B2 P19099 1/20 0.32
LMNA P02545 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23912050 0.94 ADORA2A (0.36) ADORA2AADORA1SQORELANEKDM4E
SCHEMBL20619413 0.94 ADORA1 (0.37) ADORA2AADORA1SQORELANEKDM4E
SCHEMBL23912049 0.92 ADORA2A (0.38) ADORA2AADORA1SQORELANEKDM4E
SCHEMBL23912051 0.90 SQOR (0.38) ADORA2AADORA1SQORKDM4EHPGD
SCHEMBL23912019 0.90 ALDH1A1 (0.33) SQORKDM4EHPGDCYP11B2MAPK1
SCHEMBL23912069 0.90 ALDH1A1 (0.37) ADORA2AADORA1SQORKDM4EHPGD
SCHEMBL20619417 0.89 ADORA1 (0.37) ADORA2AADORA1SQORELANEKDM4E
SCHEMBL23912036 0.87 BCHE (0.33) ADORA2AADORA1SQORELANEKDM4E
SCHEMBL23912034 0.87 ALDH1A1 (0.35) ADORA2AADORA1SQORKDM4EHPGD
SCHEMBL20619695 0.87 ADORA1 (0.36) ADORA2AADORA1SQORKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645522-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-13 EP disclosed