SCHEMBL23912059

SCHEMBL23912059

Cc1ccc2c3ccccc3n(-c3cc(-c4cccnc4)cc(-n4c5ccccc5c5ccc(C)cc54)c3C#N)c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 4/20 0.51
CYP11B1 P15538 1/20 0.44
MAOA P21397 1/20 0.44
CYP2A6 P11509 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
KDM4E B2RXH2 3/20 0.38
MAP2K4 P45985 1/20 0.38
ADORA1 P30542 2/20 0.37
HTT P42858 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.37
IKBKB O14920 1/20 0.37
ADORA2A P29274 1/20 0.37
DHODH Q02127 1/20 0.36
PDE10A Q9Y233 1/20 0.36
DYRK1A Q13627 1/20 0.36
TBXAS1 P24557 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23912058 0.95 CYP11B2 (0.47) CYP11B2CYP11B1MAOACYP2A6RXFP1
SCHEMBL23912060 0.93 CYP11B2 (0.51) CYP11B2CYP11B1MAOACYP2A6RXFP1
SCHEMBL20620035 0.92 CYP11B2 (0.47) CYP11B2CYP11B1MAOADHODHPDE10A
SCHEMBL20619578 0.91 CYP11B2 (0.56) CYP11B2CYP11B1MAOACYP2A6RXFP1
SCHEMBL20619434 0.90 CYP11B2 (0.44) CYP11B2CYP11B1MAOAKDM4EGLA
SCHEMBL23912026 0.89 CYP11B2 (0.50) CYP11B2CYP11B1MAOACYP2A6RXFP1
SCHEMBL23912078 0.89 CYP11B2 (0.46) CYP11B2CYP11B1MAOACYP2A6RXFP1
SCHEMBL23912090 0.88 CYP11B2 (0.45) CYP11B2CYP11B1MAOAKDM4EHTT
SCHEMBL19909152 0.87 CYP11B2 (0.38) CYP11B2CYP11B1MAOAKDM4EADORA1
SCHEMBL20620034 0.87 CYP11B2 (0.47) CYP11B2CYP11B1MAOACYP2A6RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645522-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-13 EP disclosed