Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 10/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912089 | 0.93 | CYP11B2 (0.45) | CYP11B2CYP11B1MAOACYP17A1CHEK1 | |
| SCHEMBL20620029 | 0.92 | CYP11B2 (0.44) | CYP11B2CYP11B1MAOACYP17A1CHEK1 | |
| SCHEMBL20620090 | 0.92 | CYP11B2 (0.47) | CYP11B2CYP11B1MAOACYP17A1DHODH | |
| SCHEMBL23912058 | 0.92 | CYP11B2 (0.47) | CYP11B2CYP11B1MAOACYP17A1KDM4E | |
| SCHEMBL23912092 | 0.91 | CYP11B2 (0.44) | CYP11B2CYP11B1MAOACYP17A1NPC1 | |
| SCHEMBL20619437 | 0.90 | CYP11B2 (0.58) | CYP11B2CYP11B1MAOACYP17A1DHODH | |
| SCHEMBL20620035 | 0.88 | CYP11B2 (0.47) | CYP11B2CYP11B1MAOACYP17A1CHEK1 | |
| SCHEMBL23912088 | 0.88 | CYP11B2 (0.41) | CYP11B2CYP11B1MAOACYP17A1NPC1 | |
| SCHEMBL23912059 | 0.88 | CYP11B2 (0.51) | CYP11B2CYP11B1MAOADHODHPDE10A | |
| SCHEMBL23912024 | 0.87 | CYP11B2 (0.48) | CYP11B2CYP11B1MAOACYP17A1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645522-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2021-10-13 | — | — | EP | disclosed |