Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619434 | 0.96 | CYP11B2 (0.44) | CYP11B2CYP11B1MAOASMN1; SMN2NPC1 | |
| SCHEMBL23912093 | 0.90 | CYP11B2 (0.44) | CYP11B2CYP11B1MAOASMN1; SMN2NPC1 | |
| SCHEMBL20620028 | 0.90 | CYP11B2 (0.44) | CYP11B2CYP11B1MAOASMN1; SMN2NPC1 | |
| SCHEMBL23912058 | 0.89 | CYP11B2 (0.47) | CYP11B2CYP11B1MAOASMN1; SMN2CYP17A1 | |
| SCHEMBL23912090 | 0.88 | CYP11B2 (0.45) | CYP11B2CYP11B1MAOANPC1RAB9A | |
| SCHEMBL20620029 | 0.87 | CYP11B2 (0.44) | CYP11B2CYP11B1MAOACYP17A1CHEK1 | |
| SCHEMBL19909057 | 0.87 | ABL1 (0.39) | CYP11B2CYP11B1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20620033 | 0.87 | CYP11B2 (0.47) | CYP11B2CYP11B1MAOASMN1; SMN2NPC1 | |
| SCHEMBL23912089 | 0.86 | CYP11B2 (0.45) | CYP11B2CYP11B1MAOACYP17A1ABL1 | |
| SCHEMBL23912059 | 0.85 | CYP11B2 (0.51) | CYP11B2CYP11B1MAOATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645522-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2021-10-13 | — | — | EP | disclosed |