Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17458216 | 0.83 | PIK3CD (0.64) | PIK3CDPIK3R1 | |
| SCHEMBL17458219 | 0.83 | PIK3CD (0.64) | PIK3CDPIK3R1 | |
| SCHEMBL17458462 | 0.82 | PIK3CD (0.66) | PIK3CDPIK3R1 | |
| SCHEMBL23912248 | 0.78 | PIK3CD (0.56) | PIK3CDSMN1; SMN2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL23912244 | 0.77 | PIK3CD (0.57) | PIK3CDSMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL17235505 | 0.76 | ESR1 (0.60) | SMN1; SMN2ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL20404396 | 0.76 | PIK3CD (0.57) | PIK3CDSMN1; SMN2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL23912309 | 0.76 | HRH3 (0.60) | PIK3CDALDH1A1KCNH2HRH3MEN1 | |
| SCHEMBL23912241 | 0.76 | HRH3 (0.60) | PIK3CDALDH1A1KCNH2HRH3MEN1 | |
| SCHEMBL23912306 | 0.74 | PIK3CD (0.56) | PIK3CDSMN1; SMN2ALDH1A1KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |